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Isolated Orbital Endodermal Sinus Tumor.

Mogaddam AS, Memar B, Aledavood A, Eslampoor A

Departments of *Ophthalmology (Khatam-Al-Anbia Eye Hospital), †Pathology (Emam Reza Hospital), and ‡Radiation Oncology (Omid Hospital), Mashhad University of Medical Sciences, Iran.

PURPOSE:: To describe the clinical, serologic, histopathologic, and immunohistochemical findings of an isolated endodermal sinus tumor of the orbit in a 1-year-old boy. METHODS:: A retrospective case report and literature review. RESULTS:: The patient was managed by the ophthalmology and oncology services. After the diagnosis was established by serologic analysis and histopathology, the patient underwent chemotherapy. CONCLUSIONS:: Endodermal sinus tumor is a malignant germ-cell tumor that usually involves the gonadal tissue. Primary extragonadal sites occur rarely, and include the orbit. Treatment options include surgical removal and chemotherapy.

Published 21 November 2007 in Ophthal Plast Reconstr Surg, 23(6): 477-479.
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